CACNG8 antibody (Middle Region)

Catalog No. ABIN2776261

Product Details anti-CACNG8 Antibody

Target: CACNG8 (Calcium Channel, Voltage-Dependent, gamma Subunit 8 (CACNG8))

Binding Specificity: Middle Region

Reactivity: Mouse, Human, Rat, Pig, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNG8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ISANAGEPGP KRDEEKKNHY SYGWSFYFGG LSFILAEVIG VLAVNIYIER

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Cacng8. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 423 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNG8

Target: CACNG8 (Calcium Channel, Voltage-Dependent, gamma Subunit 8 (CACNG8))

Alternative Name: Cacng8 (CACNG8 Products)

Synonyms: zgc:112144 antibody, calcium voltage-gated channel auxiliary subunit gamma 8 antibody, calcium channel, voltage-dependent, gamma subunit 8 antibody, calcium channel, voltage-dependent, gamma subunit 8a antibody, CACNG8 antibody, Cacng8 antibody, cacng8 antibody, cacng8a antibody

Background: Cacng8 regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). It promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Cacng8 does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Cacng8 is thought to stabilize the calcium channel in an inactivated (closed) state.
Alias Symbols: -
Protein Size: 423

Molecular Weight: 43 kDa

Gene ID: 81905

NCBI Accession: NM_133190, NP_573453

UniProt: Q8VHW2