CACNG8 antibody (Internal Region)

Catalog No. ABIN6257982

Product Details anti-CACNG8 Antibody

Target: CACNG8 (Calcium Channel, Voltage-Dependent, gamma Subunit 8 (CACNG8))

Binding Specificity: Internal Region

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNG8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: CACNG8 Antibody detects endogenous levels of total CACNG8.

Predicted Reactivity: Pig,Bovine,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CACNG8, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CACNG8

Target: CACNG8 (Calcium Channel, Voltage-Dependent, gamma Subunit 8 (CACNG8))

Alternative Name: CACNG8 (CACNG8 Products)

Synonyms: zgc:112144 antibody, calcium voltage-gated channel auxiliary subunit gamma 8 antibody, calcium channel, voltage-dependent, gamma subunit 8 antibody, calcium channel, voltage-dependent, gamma subunit 8a antibody, CACNG8 antibody, Cacng8 antibody, cacng8 antibody, cacng8a antibody

Background:

Description: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

Gene: CACNG8

Molecular Weight: 43 kDa

Gene ID: 59283

UniProt: Q8WXS5