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SMPD1 antibody (Middle Region)
SMPD1
Reactivity: Human, Mouse, Rat, Cow, Sheep, Dog, Horse, Rabbit, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SMPD1 Antibody
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Target
See all SMPD1 Antibodies
SMPD1
(Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
Binding Specificity
All epitopes for SMPD1 antibodies
Middle Region
Reactivity
All reactivities for SMPD1 antibodies
Human, Mouse, Rat, Cow, Sheep, Dog, Horse, Rabbit, Guinea Pig
Host
All hosts for SMPD1 antibodies
Rabbit
Clonality
All clonalities for SMPD1 antibodies
Polyclonal
Conjugate
All conjugates for SMPD1 antibodies
This SMPD1 antibody is un-conjugated
Application
All applications for SMPD1 antibodies
Western Blotting (WB)
Sequence
RLRDVFGWGN LTCPICKGLF TAINLGLKKE PNVARVGSVA IKLCNLLKIA
Predicted Reactivity
Cow: 83%, Dog: 87%, Guinea Pig: 87%, Horse: 80%, Human: 100%, Mouse: 80%, Rabbit: 87%, Rat: 87%, Sheep: 83%
Characteristics
This is a rabbit polyclonal antibody against SMPD1. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SMPD1
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Discover our top product SMPD1 Primary Antibody
Alternatives
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anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 396-445) antibody
SMPD1
Reactivity: Human, Mouse, Rat, Cow, Sheep, Dog, Horse, Rabbit, Pig, Bat, Monkey
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SMPD1
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Target
SMPD1
(Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
Alternative Name
SMPD1 (SMPD1 Products )
Synonyms
ASM antibody, ASMASE antibody, NPD antibody, A-SMase antibody, Zn-SMase antibody, aSMase antibody, SMPD1 antibody, sphingomyelin phosphodiesterase 1 antibody, sphingomyelin phosphodiesterase 1, acid lysosomal antibody, sphingomyelin phosphodiesterase antibody, SMPD1 antibody, Smpd1 antibody, LOC5578088 antibody
Background
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. Alias Symbols: ASM, NPD, ASMASE Protein Size: 171
Molecular Weight
18 kDa
Gene ID
6609
NCBI Accession
NM_000543 , NP_000534
UniProt
P17405
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