DDC antibody (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase)) (Middle Region)

Details for Product anti-DDC Antibody No. ABIN2776803, Supplier: Log in to see
Antigen
  • 5-HT
  • AADC
  • CG10697
  • DDC
  • DdcDm
  • Dmel\\CG10697
  • ddc
  • fDDC
  • l(2)37Bl
  • l(2)37Ch
  • l(2)k02104
  • AMD-r
  • CG10501
  • CG17345
  • Dmel\\CG10501
  • X04695
  • fAMD
  • l(2)37Bk
  • l(2)amd
  • l(2)amd alpha-methyldopa hypersensitive
  • l(2)amd[H]
  • Ddc
  • DdcDv
  • Dvir\\GJ17995
  • GJ17995
  • dvir_GLEANR_2561
  • wu:fa56d05
  • wu:fd59h03
  • wu:fk20h01
  • zgc:65801
  • zgc:76929
  • Aadc
  • Dopa decarboxylase
  • alpha methyl dopa-resistant
  • dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • dopa decarboxylase
  • Dopa-decarboxylase
  • Ddc
  • amd
  • DDC
  • ddc
  • Dvir\\Ddc
Alternatives
anti-Cow (Bovine) DDC antibody for Immunohistochemistry
Epitope
Middle Region
40
26
19
15
15
5
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
135
67
65
24
16
12
10
9
4
3
2
2
1
1
Host
Rabbit
94
36
16
3
1
Clonality
Polyclonal
Conjugate
This DDC antibody is un-conjugated
7
5
5
5
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
126
60
37
37
36
26
15
13
2
2
1
1
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human DDC
Blocking Peptide Blocking peptide for this product available: ABIN975656
Sequence SLKMWFVFRM YGVKGLQAYI RKHVQLSHEF ESLVRQDPRF EICVEVILGL
Predicted Reactivity Cow: 79%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against DDC. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name DDC (DDC Antibody Abstract)
Background DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Alias Symbols: AADC
Protein Interaction Partner: ATF6, RELA, AR,
Protein Size: 480
Molecular Weight 54 kDa
Gene ID 1644
NCBI Accession NM_000790, NP_000781
UniProt P20711
Pathways Dopaminergic Neurogenesis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 480 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (Middle Region) antibody (ABIN2776803) anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (Middle Region) antibody
Background publications Giegling, Moreno-De-Luca, Rujescu, Schneider, Hartmann, Schnabel, Maurer, Möller, Serretti: "Dopa decarboxylase and tyrosine hydroxylase gene variants in suicidal behavior." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147, Issue 3, pp. 308-15, 2008 (PubMed).

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