NADPH Oxidase 4 antibody (Middle Region)

Catalog No. ABIN2776906

Product Details anti-NADPH Oxidase 4 Antibody

Target: NADPH Oxidase 4 (NOX4)

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Sheep, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NADPH Oxidase 4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VCMVVVLFLM ITASTYAIRV SNYDIFWYTH NLFFVFYMLL TLHVSGDDWK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against NOX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NOX4

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Alternative Name: NOX4 (NOX4 Products)

Synonyms: KOX antibody, KOX-1 antibody, RENOX antibody, AI648021 antibody, nox4 antibody, NOX4 antibody, NADPH oxidase 4 antibody, NOX4 antibody, Nox4 antibody, nox4 antibody, PTRG_09562 antibody

Background: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Alias Symbols: KOX, KOX-1, RENOX
Protein Size: 342

Molecular Weight: 37 kDa

Gene ID: 50507

NCBI Accession: NM_001143836, NP_001137308

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration