SNF8, ESCRT-II Complex Subunit, Homolog (S. Cerevisiae) (SNF8) (N-Term) antibody

Details for Product No. ABIN2777633, Supplier: Log in to see
Antigen
  • d11moh34
  • vps22
  • Dot3
  • EAP30
  • VPS22
  • D11moh34
  • RGD1310144
  • D11Moh34
  • D11MOH34
  • zgc:101578
  • SNF8, ESCRT-II complex subunit
  • eap30 subunit of ell complex
  • EAP30 subunit of ELL complex
  • SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
  • snf8
  • TA17290
  • TVAG_107410
  • Bm1_05145
  • SNF8
  • Snf8
Epitope
N-Term
17
14
9
4
4
3
2
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
59
22
21
9
9
7
7
7
6
4
4
4
3
3
3
1
Host
Rabbit
44
13
1
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Immunohistochemistry (IHC), Western Blotting (WB)
55
30
9
5
2
1
1
1
Options
Supplier
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Supplier Product No.
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Blocking Peptide Blocking peptide for this product available: ABIN984183
Sequence GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT
Predicted Reactivity Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against Snf8. It was validated on Western Blot.
Purification Affinity Purified
Alternative Name Snf8 (SNF8 Antibody Abstract)
Background Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
Alias Symbols: D11moh34, MGC105799, RGD1310144
Protein Size: 258
Molecular Weight 28 kDa
Gene ID 287645
NCBI Accession NM_001007804, NP_001007805
UniProt Q5RK19
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 258 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-SNF8, ESCRT-II Complex Subunit, Homolog (S. Cerevisiae) (SNF8) (N-Term) antibody (ABIN2777633) anti-SNF8, ESCRT-II Complex Subunit, Homolog (S. Cerevisiae) (SNF8) (N-Term) antibody
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