PSMD11 antibody (C-Term)
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- Target See all PSMD11 Antibodies
- PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Horse, Guinea Pig, Rabbit, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMD11 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ALRYAGRQTE ALKCVAQASK NRSLADFEKA LTDYRAELRD DPIISTHLAK
- Cross-Reactivity
- Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PSMD11. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD11
- Top Product
- Discover our top product PSMD11 Primary Antibody
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- Application Notes
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WB Suggested Anti-PSMD11 Antibody Titration: 5.0 µg/mL
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 422 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
- Alternative Name
- PSMD11 (PSMD11 Products)
- Synonyms
- psmd11 antibody, wu:fb55b06 antibody, zgc:56580 antibody, zgc:77763 antibody, Rpn6 antibody, S9 antibody, p44.5 antibody, 1700089D09Rik antibody, 1810019E17Rik antibody, 2610024G20Rik antibody, 2810055C24Rik antibody, C78232 antibody, P44.5 antibody, proteasome 26S subunit, non-ATPase 11 antibody, proteasome 26S subunit, non-ATPase 11b antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antibody, PSMD11 antibody, psmd11b antibody, Psmd11 antibody
- Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.
Alias Symbols: S9, Rpn6, p44.5
Protein Interaction Partner: HUWE1, SUMO2, SUMO3, PSMD14, UBC, MDM2, ASB11, SHFM1, PSMC2, PSMC1, RPS8, PSMD12, PSMD8, PSMD3, PSMD1, PSMC6, PSMC5, KCMF1, PRMT6, UCHL5, KIAA0368, ADRM1, RPS21, RPS15A, PARK2, RNF11, NOS2, SMAD5, SMAD4, SMAD3, SMAD2, SMAD1, FN1, CFTR, VCAM1, LRRK2, env,
Protein Size: 422 - Molecular Weight
- 47 kDa
- Gene ID
- 5717
- NCBI Accession
- NM_002815, NP_002806
- UniProt
- O00231
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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