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TEAD4 antibody (Middle Region)

TEAD4 Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Horse, Cow, Dog WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777935
  • Target See all TEAD4 Antibodies
    TEAD4 (TEA Domain Family Member 4 (TEAD4))
    Binding Specificity
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 41
    • 24
    • 21
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Rabbit, Horse, Cow, Dog
    Host
    • 36
    • 5
    Rabbit
    Clonality
    • 38
    • 3
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEAD4 antibody is un-conjugated
    Application
    • 38
    • 13
    • 11
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    LVKFWADLNT NIEDEGSSFY GVSSQYESPE NMIITCSTKV CSFGKQVVEK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 77%
    Characteristics
    This is a rabbit polyclonal antibody against TEAD4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TEAD4
    Top Product
    Discover our top product TEAD4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 391 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Chan, Lim, Loo, Chong, Huang, Hong: "TEADs mediate nuclear retention of TAZ to promote oncogenic transformation." in: The Journal of biological chemistry, Vol. 284, Issue 21, pp. 14347-58, (2009) (PubMed).

  • Target
    TEAD4 (TEA Domain Family Member 4 (TEAD4))
    Alternative Name
    TEAD4 (TEAD4 Products)
    Synonyms
    TEAD4 antibody, rtef1 antibody, tef-3 antibody, eftr-2 antibody, tefr-1 antibody, tcf13l1 antibody, hrtef-1b antibody, xdtef-1 antibody, xlDTEF-1 antibody, RTEF-1 antibody, TEF-1 antibody, TEF-3 antibody, EFTR-2 antibody, RTEF1 antibody, TCF13L1 antibody, TEF3 antibody, TEFR-1 antibody, hRTEF-1B antibody, ETFR-2 antibody, Etfr2 antibody, FR-19 antibody, TEAD-4 antibody, Tcf13r1 antibody, Tef3 antibody, Tefr antibody, Tefr1 antibody, Tefr1a antibody, TEA domain transcription factor 4 antibody, TEA domain transcription factor 4 S homeolog antibody, TEA domain family member 4 antibody, TEAD4 antibody, tead4 antibody, tead4.S antibody, Tead4 antibody
    Background
    TEAD4 is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this protein.This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
    Alias Symbols: EFTR-2, MGC9014, RTEF1, TCF13L1, TEF-3, TEFR-1, hRTEF-1B, TEF3
    Protein Interaction Partner: CCDC172, SSX2IP, LZTS2, CEP70, CEP55, RABGEF1, CCNDBP1, KIAA0753, PNMA1, TRAF1, VPS52, TRIM27, GOLGA2, UBC, SUMO2, CCDC85B, WWTR1, YAP1, VGLL1, MYH7,
    Protein Size: 391
    Molecular Weight
    44 kDa
    Gene ID
    7004
    NCBI Accession
    NM_201441, NP_958849
    UniProt
    Q15561
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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