TGFB1I1 antibody (Middle Region)

Catalog No. ABIN2777947

Product Details anti-TGFB1I1 Antibody

Target: TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFB1I1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PEPTGKGSLD TMLGLLQSDL SRRGVPTQAK GLCGSCNKPI AGQVVTALGR

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TGFB1I1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TGFB1I1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 444 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TGFB1I1 antibody (ABIN2777947)

Miyoshi, Ishiguro, Uemura, Fujinami, Miyamoto, Miyoshi, Kitamura, Kubota: "Expression of AR associated protein 55 (ARA55) and androgen receptor in prostate cancer." in: The Prostate, Vol. 56, Issue 4, pp. 280-6, (2003) (PubMed).

Target Details for TGFB1I1

Target: TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))

Alternative Name: TGFB1I1 (TGFB1I1 Products)

Synonyms: TGFB1I1 antibody, hic5 antibody, ara55 antibody, hic-5 antibody, tsc-5 antibody, ARA55 antibody, HIC-5 antibody, HIC5 antibody, TSC-5 antibody, Hic5 antibody, Ara55 antibody, Hic-5 antibody, ara-55 antibody, transforming growth factor beta 1 induced transcript 1 antibody, transforming growth factor beta 1 induced transcript 1 L homeolog antibody, TGFB1I1 antibody, tgfb1i1 antibody, Tgfb1i1 antibody, tgfb1i1.L antibody

Background: The TGFB1I1 gene encodes a protein that is a key element in the transduction of signals from the cell surface to the nucleus under oxidative stress-review. Higher gene expression may result in unfavorable recurrence-free survival and overall survival in hormone-refractory prostate cancer.
Alias Symbols: ARA55, HIC-5, HIC5, TSC-5
Protein Interaction Partner: HSPB2, HSPB1, CBLC, SMAD4, SMAD3, Pparg, CDKN2B, PLA2G3, HIPK3, CBLB, NCF1, GP6, TRAF4, SMAD7, GP1BB, UBQLN4, NEDD4L, UBC, PTK2, MAPK15, GIT2, SDC4, GIT1, SVIL, EP300, CRKL, PTK2B, PTPN12, AR, ITGA4, TGFBR2, FKBP1A, NR3C1, SLC6A3, VCL, CSK, PXN, CCNA1, VH
Protein Size: 444

Molecular Weight: 48 kDa

Gene ID: 7041

NCBI Accession: NM_015927, NP_057011

UniProt: B2R8D5

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, VEGF Signaling