FOXP2 antibody (Forkhead Box P2) (N-Term)

Details for Product anti-FOXP2 Antibody No. ABIN2778104, Supplier: Log in to see
Antigen
  • spch1
  • cagh44
  • tnrc10
  • xlFoxP2
  • FOXP2
  • foxP2
  • foxP
  • Foxp2
  • CAGH44
  • SPCH1
  • TNRC10
  • 2810043D05Rik
  • AI449000
  • CAG-16
  • D0Kist7
  • RGD1559697
  • foxP2b
  • foxp2a
  • forkhead box P2
  • lmw-gs
  • forkhead box transcription factor
  • forkhead box P2 (predicted), 5 prime
  • uncharacterized LOC505502
  • FOXP2
  • foxp2
  • LOC100144325
  • LOC100169841
  • foxP2
  • Foxp2
  • foxp1c
  • LOC505502
Epitope
N-Term
34
15
11
7
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Goat, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish
126
50
30
9
9
6
6
4
4
3
2
2
2
2
1
1
Host
Rabbit
59
37
31
1
Clonality
Polyclonal
Conjugate
This FOXP2 antibody is un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (IHC), Western Blotting (WB)
112
79
31
24
14
11
3
2
2
2
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP2
Blocking Peptide Blocking peptide for this product available: ABIN977077
Sequence SGLKSPKSSD KQRPLQVPVS VAMMTPQVIT PQQMQQILQQ QVLSPQQLQA
Specificity Isoform 4 and 5
Predicted Reactivity Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
Characteristics This is a rabbit polyclonal antibody against FOXP2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FOXP2 (FOXP2 Antibody Abstract)
Background FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.
Alias Symbols: SPCH1, CAGH44, TNRC10
Protein Interaction Partner: FAM124A, TSACC, RPIA, SP4, SDCBP, PIN1, CTBP2, CTBP1, CCNC, AES, MAPK3, HSP90AA1, GATAD2B, FOXP1, FOXP4, FOXP2,
Protein Size: 715
Molecular Weight 80 kDa
Gene ID 93986
NCBI Accession NM_014491, NP_055306
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 715 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Forkhead Box P2 (FOXP2) (N-Term) antibody (ABIN2778104) anti-Forkhead Box P2 (FOXP2) (N-Term) antibody
Western Blotting (WB) image for anti-Forkhead Box P2 (FOXP2) (N-Term) antibody (ABIN2778104) anti-Forkhead Box P2 (FOXP2) (N-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Forkhead Box P2 (FOXP2) (N-Term) antibody (ABIN2778104) anti-Forkhead Box P2 (FOXP2) (N-Term) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-Forkhead Box P2 (FOXP2) (N-Term) antibody (ABIN2778104) Rabbit Anti-FOXP2 Antibody Catalog Number: ARP33750 Paraffin Embedded Tissue: Human K...
Background publications Sanjuán, Tolosa, González, Aguilar, Pérez-Tur, Nájera, Moltó, de Frutos: "Association between FOXP2 polymorphisms and schizophrenia with auditory hallucinations." in: Psychiatric genetics, Vol. 16, Issue 2, pp. 67-72, 2006 (PubMed).