Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

FOXP2 Products

(Forkhead Box P2 (FOXP2))

Categories

This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured FOXP2 Categories

FOXP2 Antibodies

High quality antibodies with extensive validation data.

FOXP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FOXP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (5)
  • (4)
Cat. No. ABIN263146
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, ICC, IHC, WB
Validations
  • (5)
Cat. No. ABIN5542318
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN334400
Quantity 100 μg
Datasheet Datasheet

Recommended FOXP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6204404
Quantity 96 tests
Datasheet Datasheet

Recommended FOXP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134540
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092623
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354389
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our FOXP2 products

Willett, Bayin, Lee, Krishnamurthy, Wojcinski, Lao, Stephen, Rosello-Diez, Dauber-Decker, Orvis, Wu, Tessier-Lavigne, Joyner: "Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth." in: eLife, Vol. 8, (2020) (PubMed).

Plaas, Seppa, Reimets, Jagomäe, Toots, Koppel, Vallisoo, Nigul, Heinla, Meier, Kaasik, Piirsoo, Hickey, Terasmaa, Vasar: "Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration." in: Scientific reports, Vol. 7, Issue 1, pp. 10220, (2019) (PubMed).

Vibulyaseck, Fujita, Luo, Tran, Oh-Nishi, Ono, Hirano, Sugihara: "Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum." in: The Journal of comparative neurology, Vol. 525, Issue 14, pp. 2971-2990, (2018) (PubMed).

Haldipur, Dang, Aldinger, Janson, Guimiot, Adle-Biasette, Dobyns, Siebert, Russo, Millen: "Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms." in: eLife, Vol. 6, (2017) (PubMed).

Abdi, Mallet, Mohamed, Sharott, Dodson, Nakamura, Suri, Avery, Larvin, Garas, Garas, Vinciati, Morin, Bezard, Baufreton, Magill: "Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 17, pp. 6667-88, (2015) (PubMed).

Brunjes, Osterberg: "Developmental Markers Expressed in Neocortical Layers Are Differentially Exhibited in Olfactory Cortex." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138541, (2015) (PubMed).

Cuiffo, Campagne, Bell, Lembo, Orso, Lien, Bhasin, Raimo, Hanson, Marusyk, El-Ashry, Hematti, Polyak, Mechta-Grigoriou, Mariani, Volinia, Vincent-Salomon, Taverna, Karnoub: "MSC-regulated microRNAs converge on the transcription factor FOXP2 and promote breast cancer metastasis." in: Cell stem cell, Vol. 15, Issue 6, pp. 762-74, (2014) (PubMed).

Duque, Gazula, Kaczmarek: "Expression of Kv1.3 potassium channels regulates density of cortical interneurons." in: Developmental neurobiology, Vol. 73, Issue 11, pp. 841-55, (2013) (PubMed).

Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

Lee, Shull, Frappart, Katyal, Enriquez-Rios, Zhao, Russell, Brown, McKinnon: "ATR maintains select progenitors during nervous system development." in: The EMBO journal, Vol. 31, Issue 5, pp. 1177-89, (2012) (PubMed).

Synonyms and alternative names related to FOXP2

forkhead box P2 (FOXP2), forkhead box P2 (Foxp2), forkhead box P2 (foxp2), forkhead box P2 (foxP2), lmw-gs (Foxp2), forkhead box transcription factor (foxp1c), forkhead box P2 L homeolog (foxp2.L), 2810043D05Rik, AI449000, CAG-16, CAGH44, cagh44, D0Kist7, foxP, FOXP2, foxP2, Foxp2, foxp2a, foxP2b, RGD1559697, SPCH1, spch1, TNRC10, tnrc10, xlFoxP2

Protein level used designations for FOXP2

  • CAG repeat protein 44
  • forkhead box protein P2
  • forkhead/winged-helix transcription factor
  • trinucleotide repeat containing 10
  • trinucleotide repeat-containing gene 10 protein
  • forkhead box P2
  • transcription factor FoxP2
  • forkhead box P protein
  • lmw-gs
  • forkhead box transcription factor
  • xlFoxP2
You are here:
Support