Fetuin A antibody (alpha-2-HS-Glycoprotein) (N-Term)

Details for Product anti-AHSG Antibody No. ABIN2778140, Supplier: Log in to see
Antigen
  • ahs
  • a2hs
  • hsga
  • fetua
  • wu:fb63g02
  • zgc:103687
  • AHSG
  • MGC116429
  • A2HS
  • AHS
  • FETUA
  • HSGA
  • Aa2-066
  • pp63
  • alpha-2-HS-glycoprotein
  • FETUIN protein
  • Cphamn1_1981
  • AHSG
  • ahsg
  • Ahsg
  • FETUIN
Epitope
N-Term
15
15
15
14
12
10
8
7
7
5
5
3
2
2
2
1
1
1
1
Reactivity
Dog (Canine), Guinea Pig, Horse (Equine), Human, Rat (Rattus)
168
53
28
7
2
1
1
1
Host
Rabbit
128
25
24
18
15
3
Clonality
Polyclonal
Conjugate
This Fetuin A antibody is un-conjugated
15
13
8
6
6
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
151
102
60
33
32
25
19
16
13
11
6
2
2
1
1
1
1
1
1
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human AHSG
Blocking Peptide Blocking peptide for this product available: ABIN973024
Sequence AQLWGCHSAP HGPGLIYRQP NCDDPETEEA ALVAIDYINQ NLPWGYKHTL
Predicted Reactivity Dog: 86%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against AHSG. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name AHSG (AHSG Antibody Abstract)
Background Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: A2HS, AHS, FETUA, HSGA
Protein Interaction Partner: SUMO1, UBC, NEDD8, ATF2, ALB, VKORC1, PPP5C, FBXO2, PSMA3, GRB2, CDC42, Mad2l1, Smad3, Hsd17b7, RRAS2, INSR, DCN,
Protein Size: 367
Molecular Weight 39 kDa
Gene ID 197
NCBI Accession NM_001622, NP_001613
UniProt P02765
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 367 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-alpha-2-HS-Glycoprotein (AHSG) (N-Term) antibody (ABIN2778140) anti-alpha-2-HS-Glycoprotein (AHSG) (N-Term) antibody
Product cited in: Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, 2014 (PubMed).

Gil-Dones, Darde, Alonso-Orgaz, Lopez-Almodovar, Mourino-Alvarez, Padial, Vivanco, Barderas: "Inside human aortic stenosis: a proteomic analysis of plasma." in: Journal of proteomics, Vol. 75, Issue 5, pp. 1639-53, 2012 (PubMed).

Background publications Ix, Shlipak, Brandenburg, Ali, Ketteler, Whooley: "Association between human fetuin-A and the metabolic syndrome: data from the Heart and Soul Study." in: Circulation, Vol. 113, Issue 14, pp. 1760-7, 2006 (PubMed).

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