SPINK1 antibody (N-Term)
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- Target See all SPINK1 Antibodies
- SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPINK1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KVTGIFLLSA LALLSLSGNT GADSLGREAK CYNELNGCTK IYDPVCGTDG
- Predicted Reactivity
- Human: 100%, Rabbit: 93%
- Characteristics
- This is a rabbit polyclonal antibody against SPINK1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SPINK1
- Top Product
- Discover our top product SPINK1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 79 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The role of SPINK1 in ETS rearrangement-negative prostate cancers. ..." in: Cancer cell, Vol. 13, Issue 6, pp. 519-28, (2008) (PubMed).
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The role of SPINK1 in ETS rearrangement-negative prostate cancers. ..." in: Cancer cell, Vol. 13, Issue 6, pp. 519-28, (2008) (PubMed).
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- Target
- SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
- Alternative Name
- SPINK1 (SPINK1 Products)
- Synonyms
- PCTT antibody, PSTI antibody, Spink3 antibody, TATI antibody, TCP antibody, Psti antibody, SPINK1 antibody, p12 antibody, serine peptidase inhibitor, Kazal type 1 antibody, SPINK1 antibody, Spink1 antibody
- Background
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SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.
Alias Symbols: PCTT, PSTI, Spink3, TATI, TCP
Protein Interaction Partner: NRSN1, TMPRSS15, CTRC, ELN,
Protein Size: 79 - Molecular Weight
- 8 kDa
- Gene ID
- 6690
- NCBI Accession
- NM_003122, NP_003113
- UniProt
- P00995
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