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MXD3 antibody (N-Term)

MXD3 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig, Zebrafish (Danio rerio), Sheep WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778375
  • Target See all MXD3 Antibodies
    MXD3 (MAX Dimerization Protein 3 (MXD3))
    Binding Specificity
    • 10
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 37
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig, Zebrafish (Danio rerio), Sheep
    Host
    • 34
    • 3
    • 1
    Rabbit
    Clonality
    • 34
    • 4
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MXD3 antibody is un-conjugated
    Application
    • 24
    • 19
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    MEPLASNIQV LLQAAEFLER REREAEHGYA SLCPHRSPGP IHRRKKRPPQ
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against MXD3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human MXD3
    Top Product
    Discover our top product MXD3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 206 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MXD3 (MAX Dimerization Protein 3 (MXD3))
    Alternative Name
    MXD3 (MXD3 Products)
    Synonyms
    Mad3 antibody, BHLHC13 antibody, MAD3 antibody, MYX antibody, 4631412E13Rik antibody, bHLHc13 antibody, Mad antibody, zgc:66281 antibody, Myx antibody, MAX dimerization protein 3 antibody, Max dimerization protein 3 antibody, MAX dimerization protein 3 L homeolog antibody, mxd3 antibody, MXD3 antibody, Mxd3 antibody, mxd3.L antibody
    Background
    MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
    Alias Symbols: MAD3, MGC2383, MYX, BHLHC13
    Protein Interaction Partner: NOTCH2NL, KRTAP10-7, UBC, NFKB1, MAGEA11, MAX, SIN3A, SMC3,
    Protein Size: 206
    Molecular Weight
    23 kDa
    Gene ID
    83463
    NCBI Accession
    NM_031300, NP_112590
    UniProt
    Q9BW11
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