Protein Arginine Methyltransferase 6 (PRMT6) (Middle Region) antibody

Details for Product No. ABIN2778658, Supplier: Log in to see
Antigen
  • CG9927
  • DART6
  • Dmel\\CG9927
  • PRMT6
  • HRMT1L6
  • ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6
  • ATPRMT6
  • protein arginine methyltransferase 6
  • DKFZp459B1431
  • Hrmt1l6
  • hrmt1l6
  • hrmt6
  • im:6908706
  • AW124876
  • BB233495
  • Arginine methyltransferase 6
  • protein arginine methyltransferase 6
  • protein arginine N-methyltransferase 6
  • arginine N-methyltransferase, type I
  • Art6
  • PRMT6
  • prmt6
  • Prmt6
Epitope
Middle Region
8
7
6
6
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus)
98
23
21
14
6
5
4
4
2
1
1
Host
Rabbit
59
25
15
1
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
88
38
24
15
11
7
7
2
2
2
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PRMT6
Blocking Peptide Blocking peptide for this product available: ABIN982239
Sequence FRCSCYGSAP MHGFAIWFQV TFPGGESEKP LVLSTSPFHP ATHWKQALLY
Predicted Reactivity Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against PRMT6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PRMT6 (PRMT6 Antibody Abstract)
Background Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.[supplied by OMIM].
Alias Symbols: FLJ10559, HRMT1L6
Protein Interaction Partner: KIF9, RASSF2, KIAA0408, DNAJA3, AP1G2, HESX1, BLZF1, DNALI1, ZSCAN9, TSC1, TDO2, SUV39H1, SMARCD1, RAD17, RAC1, PSMD11, PEX7, OAS1, NEFL, MNDA, SMAD9, ID2, HOXC4, HOXA5, HOXA1, HNRNPH2, GBE1, FYN, DXO, BMP3, BCAT1, H3F3C, C17orf82, THEMIS, C8orf74, AK8, W
Protein Size: 316
Molecular Weight 35 kDa
Gene ID 55170
NCBI Accession NM_018137, NP_060607
UniProt A3KME1
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 316 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Protein Arginine Methyltransferase 6 (PRMT6) (Middle Region) antibody (ABIN2778658) WB Suggested Anti-PRMT6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Chromatin Immunoprecipitation (ChIP) image for anti-Protein Arginine Methyltransferase 6 (PRMT6) (Middle Region) antibody (ABIN2778658) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
Background publications Iberg, Espejo, Cheng, Kim, Michaud-Levesque, Richard, Bedford: "Arginine methylation of the histone H3 tail impedes effector binding." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3006-10, 2008 (PubMed).