TAF15 antibody (N-Term)
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- Target See all TAF15 Antibodies
- TAF15 (TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAF15 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PDYGQQDSYD QQSGYDQHQG SYDEQSNYDQ QHDSYSQNQQ SYHSQRENYS
- Predicted Reactivity
- Cow: 93%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%, Yeast: 89%
- Characteristics
- This is a rabbit polyclonal antibody against TAF15. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TAF15
- Top Product
- Discover our top product TAF15 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 592 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TAF15 (TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15))
- Alternative Name
- TAF15 (TAF15 Products)
- Synonyms
- 2610111C21Rik antibody, 68kDa antibody, TAFII68 antibody, Taf2n antibody, Npl3 antibody, RBP56 antibody, TAF2N antibody, TATA-box binding protein associated factor 15 antibody, Taf15 antibody, TAF15 antibody
- Background
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. Its gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.
Alias Symbols: Npl3, RBP56, TAF2N, TAFII68, hTAFII68
Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, EED, UBD, PRMT8, MED26, UBC, FUS, TPR, TPM2, DDB1, SCARB2, RNF168, TMED9, SAP30BP, NEDD8, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, YWHAZ, SIRT7, HIST2H4A, HIST1H3A, HIST2H2AC, CACNA1A,
Protein Size: 592 - Molecular Weight
- 62 kDa
- Gene ID
- 8148
- NCBI Accession
- NM_139215, NP_631961
- UniProt
- Q92804
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