KHSRP antibody (Middle Region)
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- Target See all KHSRP Antibodies
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KHSRP antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- WEEYYKKQAQ VATGGGPGAP PGSQPDYSAA WAEYYRQQAA YYGQTPGPGG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against KHSRP. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human KHSRP
- Top Product
- Discover our top product KHSRP Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 711 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Electrophilic tuning of the chemoprotective natural product sulforaphane." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 21, pp. 9590-5, (2010) (PubMed).
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Electrophilic tuning of the chemoprotective natural product sulforaphane." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 21, pp. 9590-5, (2010) (PubMed).
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- Target
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
- Alternative Name
- KHSRP (KHSRP Products)
- Synonyms
- FBP2 antibody, FUBP2 antibody, KSRP antibody, 6330409F21Rik antibody, Fbp2 antibody, Fubp2 antibody, Ksrp antibody, Marta1 antibody, KHSRP antibody, VgRBP71 antibody, fbp2 antibody, ksrp antibody, fubp2 antibody, fc94c12 antibody, wu:fb25b12 antibody, wu:fc10e10 antibody, wu:fc94c12 antibody, zgc:163038 antibody, khsrp-b antibody, KH-type splicing regulatory protein antibody, KH-type splicing regulatory protein L homeolog antibody, KH-type splicing regulatory protein S homeolog antibody, KHSRP antibody, Khsrp antibody, khsrp.L antibody, khsrp antibody, khsrp.S antibody
- Background
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KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE).It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Alias Symbols: FBP2, FUBP2, KSRP, MGC99676
Protein Interaction Partner: HUWE1, Bace1, UBC, STAU1, LGR4, MDM2, WWOX, SUZ12, EED, RNF2, NAP1L4, HNRNPD, GFPT1, GARS, APBB1, ALDH16A1, TARDBP, CD81, MPG, UBL4A, WHSC1, VCAM1, ITGA4, FN1, STRIP1, ASF1B, CPLX1, CIRBP, SUMO1, RAE1, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD8, C
Protein Size: 711 - Molecular Weight
- 73 kDa
- Gene ID
- 8570
- NCBI Accession
- NM_003685, NP_003676
- UniProt
- Q92945
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