TARBP2 antibody (N-Term)

Catalog No. ABIN2778885

Product Details anti-TARBP2 Antibody

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Horse, Rabbit, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ANPGKTPISL LQEYGTRIGK TPVYDLLKAE GQAHQPNFTF RVTVGDTSCT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TARBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TARBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 74 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TARBP2

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Alternative Name: TARBP2 (TARBP2 Products)

Synonyms: trbp antibody, trbp1 antibody, trbp2 antibody, MGC97783 antibody, TARBP2 antibody, LOQS antibody, TRBP antibody, TRBP1 antibody, TRBP2 antibody, fj51e12 antibody, wu:fj51e12 antibody, zgc:63778 antibody, Prbp antibody, TAR (HIV-1) RNA binding protein 2 antibody, TARBP2, RISC loading complex RNA binding subunit antibody, TAR (HIV-1) RNA binding protein 2 L homeolog antibody, TAR (HIV) RNA binding protein 2 antibody, tarbp2 antibody, TARBP2 antibody, tarbp2.L antibody, Tarbp2 antibody

Background: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARBP2 binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein.
Alias Symbols: LOQS, TRBP, TRBP1, TRBP2
Protein Interaction Partner: TCEANC, STRBP, ZNF346, PRKRA, TARBP2, RRP12, RRP1B, POP1, CEBPZ, RRP9, AGO3, C1orf35, DDX50, NOC3L, TSR1, DDX27, AKAP17A, TCOF1, SRPR, SRP72, SRP54, TRMT1, SDAD1, RBM28, GPATCH4, HP1BP3, AGO2, DICER1, NUDT18, AGO1, APP, TOP1, CUL3, VAV2, NEDD4L, EIF2AK2,
Protein Size: 74

Molecular Weight: 8 kDa

Gene ID: 6895

NCBI Accession: NM_004178

UniProt: Q8WY33

Pathways: Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization