TROVE2 antibody (TROVE Domain Family, Member 2) (N-Term)

Details for Product anti-TROVE2 Antibody No. ABIN2778905, Supplier: Log in to see
Antigen
  • SSA2
  • TROVE2
  • ssa2
  • ssa2-A
  • RO60
  • RORNP
  • 1810007I17Rik
  • A530054J02Rik
  • AI646302
  • SS-A/Ro
  • Ssa
  • Ssa2
  • TROVE domain family, member 2
  • TROVE2
  • LOC100232542
  • trove2
  • Trove2
Epitope
N-Term
11
10
10
8
4
4
4
3
3
3
3
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
107
33
27
5
4
3
2
2
2
1
1
Host
Rabbit
86
21
Clonality
Polyclonal
Conjugate
This TROVE2 antibody is un-conjugated
7
7
7
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
87
50
19
13
13
7
3
2
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TROVE2
Blocking Peptide Blocking peptide for this product available: ABIN985617
Sequence QDGYVWQVTD MNRLHRFLCF GSEGGTYYIK EQKLGLENAE ALIRLIEDGR
Predicted Reactivity Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against TROVE2. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name TROVE2 (TROVE2 Antibody Abstract)
Background TROVE2 belongs to the Ro 60 kDa family. It is RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. It may stabilize these RNAs from degradation.
Alias Symbols: RO60, SSA2, RORNP
Protein Interaction Partner: UBC, JMJD6, XPO7, PUF60, FAF1, SEC23A, PRMT3, RANBP3, HIRIP3, HIST1H4A, SF1, UGP2, RPL24, PPM1G, PPAT, HSPA4, GFPT1, GART, GARS, CARS, METTL18, PAGR1, TEP1, SSB, TRIM21, CUL3, RAB11FIP5,
Protein Size: 525
Molecular Weight 58 kDa
Gene ID 6738
NCBI Accession NM_001042369, NP_001035828
UniProt P10155
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 525 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-TROVE2 antibody (TROVE Domain Family, Member 2) (N-Term) (ABIN2778905) WB Suggested Anti-TROVE2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-TROVE2 antibody (TROVE Domain Family, Member 2) (N-Term) (ABIN2778905) anti-TROVE Domain Family, Member 2 (TROVE2) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-TROVE2 antibody (TROVE Domain Family, Member 2) (N-Term) (ABIN2778905) WB Suggested Anti-TROVE2
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500...
Background publications Hennig, Ottosson, Andrésen, Horvath, Kuchroo, Broo, Wahren-Herlenius, Sunnerhagen: "Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52." in: The Journal of biological chemistry, Vol. 280, Issue 39, pp. 33250-61, 2005 (PubMed).