SF3A3 antibody (Middle Region)
-
- Target See all SF3A3 Antibodies
- SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Dog, Horse, Guinea Pig, Saccharomyces cerevisiae
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SF3A3 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- THENVQRKQA RTGEEREEEE EEQISESESE DEENEIIYNP KNLPLGWDGK
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 91%
- Characteristics
- This is a rabbit polyclonal antibody against SF3A3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SF3A3
- Top Product
- Discover our top product SF3A3 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 501 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "
-
Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
-
- Target
- SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))
- Alternative Name
- SF3A3 (SF3A3 Products)
- Synonyms
- PRP9 antibody, PRPF9 antibody, SAP61 antibody, SF3a60 antibody, 4930512K19Rik antibody, 60kDa antibody, LRRGT00093 antibody, wu:fi15a06 antibody, wu:fj94f01 antibody, zgc:110227 antibody, splicing factor 3a subunit 3 antibody, splicing factor 3a, subunit 3, 60kDa antibody, splicing factor 3a, subunit 3 antibody, splicing factor 3a subunit 3 S homeolog antibody, SF3A3 antibody, Sf3a3 antibody, sf3a3.S antibody, sf3a3 antibody
- Background
-
SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PRP9, PRPF9, SAP61, SF3a60
Protein Interaction Partner: TRIM69, HUWE1, ZNF212, TADA2A, FUS, UBC, NEDD8, MDM2, WWOX, RNF2, SUZ12, EED, rev, APBB1, ACTN1, ACTN4, STAM2, HGS, SNRPB, CDAN1, PRPF40A, WBP4, TCERG1, UBD, SF3A1, FN1, gag-pol, PRMT5, PRPF19, PRPF31, SF3B1, SF3B3, SF3B4, HNRNPR, DDX46, TOX4, DDX23, PRPF
Protein Size: 501 - Molecular Weight
- 59 kDa
- Gene ID
- 10946
- NCBI Accession
- NM_006802, NP_006793
- UniProt
- Q12874
- Pathways
- Ribonucleoprotein Complex Subunit Organization
-