CPSF6 antibody (Middle Region)
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- Target See all CPSF6 Antibodies
- CPSF6 (Cleavage and Polyadenylation Specific Factor 6, 68kDa (CPSF6))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio), Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CPSF6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- PPLAGPPNRG DRPPPPVLFP GQPFGQPPLG PLPPGPPPPV PGYGPPPGPP
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against CPSF6. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CPSF6
- Top Product
- Discover our top product CPSF6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 551 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CPSF6 (Cleavage and Polyadenylation Specific Factor 6, 68kDa (CPSF6))
- Alternative Name
- CPSF6 (CPSF6 Products)
- Synonyms
- CPSF6 antibody, wu:fa22f12 antibody, zgc:85819 antibody, 4733401N12Rik antibody, AI256641 antibody, CFIM antibody, CFIM68 antibody, HPBRII-4 antibody, HPBRII-7 antibody, cleavage and polyadenylation specific factor 6 antibody, cleavage and polyadenylation specific factor 6 S homeolog antibody, CPSF6 antibody, cpsf6.S antibody, cpsf6 antibody, Cpsf6 antibody
- Background
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CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides.The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
Alias Symbols: CFIM, CFIM68, HPBRII-4, HPBRII-7
Protein Interaction Partner: ARMC7, OTUB2, TOLLIP, PPIL1, FUS, FXR2, WWOX, EZH2, SUZ12, EED, rev, ITCH, PRPF40A, WBP4, TCERG1, NEDD4, APBB1, SRPK2, WWP1, NUDT21, LMNA, CD81, TP63, UBC, NPM1, FN1, DAB2, CSNK2A1, SMURF1, BARD1, MDC1, ZBTB8B, CPSF7, NUP107, TBC1D2, WBP11, PUF60, U2AF2,
Protein Size: 551 - Molecular Weight
- 61 kDa
- Gene ID
- 11052
- NCBI Accession
- NM_007007, NP_008938
- UniProt
- Q16630
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