SREBF1 antibody (N-Term)
-
- Target See all SREBF1 Antibodies
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
-
Binding Specificity
- N-Term
-
Reactivity
- Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SREBF1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- DIEDMLQLIN NQDSDFPGLF DAPYAGGETG DTGPSSPGAN SPESFSSASL
- Predicted Reactivity
- Mouse: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against SREBF1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse SREBF1
- Top Product
- Discover our top product SREBF1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 1134 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
- Alternative Name
- SREBF1 (SREBF1 Products)
- Synonyms
- SREBP-1c antibody, SREBP1 antibody, bHLHd1 antibody, ADD-1 antibody, ADD1 antibody, D630008H06 antibody, SREBP-1 antibody, SREBP-1a antibody, SREBP1c antibody, Srebp1 antibody, SCREBP1 antibody, SREBP-1C antibody, SREBF1 antibody, srebp1 antibody, sterol regulatory element binding transcription factor 1 antibody, sterol regulatory element binding transcription factor 1 L homeolog antibody, sterol regulatory element binding protein-1 antibody, Sterol regulatory element Binding Protein antibody, SREBF1 antibody, Srebf1 antibody, srebf1.L antibody, SREBP-1 antibody, srebf1 antibody, sbp-1 antibody
- Background
-
Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3'). Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene.
Alias Symbols: ADD1, ADD-1, SREBP1, bHLHd1, SREBP-1, SREBP1c, SREBP-1a, SREBP-1c, D630008H06
Protein Interaction Partner: Rnf20, Zbtb7c, Ppargc1b, Rela, Ewsr1, Pcbd1,
Protein Size: 1134 - Molecular Weight
- 125 kDa
- Gene ID
- 20787
- NCBI Accession
- NM_011480, NP_035610
- UniProt
- Q9WTN3
- Pathways
- AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
-