KLHL12 antibody (N-Term)

Catalog No. ABIN2781157

Product Details anti-KLHL12 Antibody

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DIMTNTHAKS ILNSMNSLRK SNTLCDVTLR VEQKDFPAHR IVLAACSDYF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against Klhl12. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 568 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KLHL12

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Alternative Name: Klhl12 (KLHL12 Products)

Synonyms: zgc:92570 antibody, wu:fi60g03 antibody, C3ip1 antibody, C3IP1 antibody, DKIR antibody, hDKIR antibody, Ski2 like RNA helicase antibody, kelch like family member 12 L homeolog antibody, kelch like family member 12 antibody, kelch-like family member 12 antibody, kelch-like 12 antibody, SKIV2L antibody, klhl12.L antibody, KLHL12 antibody, klhl12 antibody, Klhl12 antibody

Background: Klhl12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
Alias Symbols: C3ip1, MGC93127
Protein Size: 568

Molecular Weight: 62 kDa

Gene ID: 266772

NCBI Accession: NM_153730, NP_714952

UniProt: Q8R2H4