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KLHL12 antibody (N-Term)

KLHL12 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781157
  • Target See all KLHL12 Antibodies
    KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 38
    • 28
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig
    Host
    • 48
    • 4
    • 1
    Rabbit
    Clonality
    • 50
    • 3
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLHL12 antibody is un-conjugated
    Application
    • 40
    • 21
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    DIMTNTHAKS ILNSMNSLRK SNTLCDVTLR VEQKDFPAHR IVLAACSDYF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against Klhl12. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product KLHL12 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 568 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
    Alternative Name
    Klhl12 (KLHL12 Products)
    Synonyms
    zgc:92570 antibody, wu:fi60g03 antibody, C3ip1 antibody, C3IP1 antibody, DKIR antibody, hDKIR antibody, Ski2 like RNA helicase antibody, kelch like family member 12 L homeolog antibody, kelch like family member 12 antibody, kelch-like family member 12 antibody, kelch-like 12 antibody, SKIV2L antibody, klhl12.L antibody, KLHL12 antibody, klhl12 antibody, Klhl12 antibody
    Background
    Klhl12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
    Alias Symbols: C3ip1, MGC93127
    Protein Size: 568
    Molecular Weight
    62 kDa
    Gene ID
    266772
    NCBI Accession
    NM_153730, NP_714952
    UniProt
    Q8R2H4
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