ABCA1 antibody (Middle Region)
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- Target See all ABCA1 Antibodies
- ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
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Binding Specificity
- Middle Region
- Reactivity
- Mouse, Human, Rat, Guinea Pig, Dog, Cow, Horse, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ABCA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NRRAFGDKQS CLHPFTEDDA VDPNDSDIDP ESRETDLLSG MDGKGSYQLK
- Predicted Reactivity
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against Abca1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product ABCA1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 2261 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).
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ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).
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- Target
- ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
- Alternative Name
- Abca1 (ABCA1 Products)
- Synonyms
- ABC-1 antibody, ABC1 antibody, CERP antibody, HDLDT1 antibody, TGD antibody, ABCA1 antibody, Abc1 antibody, ATP-binding cassette A1 antibody, Arabidopsis thaliana ATP-binding cassette A1 antibody, AtABCA1 antibody, im:7136239 antibody, sb:cb407 antibody, wu:fa07e06 antibody, zgc:171581 antibody, ATP binding cassette subfamily A member 1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1 antibody, ATP-binding cassette A1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1B antibody, ABCA1 antibody, Abca1 antibody, abca1 antibody, abca1b antibody
- Background
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Abca1 is a cAMP-dependent and sulfonylurea-sensitive anion transporter. Abca1 is a key gatekeeper influencing intracellular cholesterol transport.
Alias Symbols: Abc1
Protein Interaction Partner: Sptlc1, Ubc,
Protein Size: 2261 - Molecular Weight
- 254 kDa
- Gene ID
- 11303
- NCBI Accession
- NM_013454, NP_038482
- UniProt
- B1AWZ8
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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