NAT2 antibody (Middle Region)
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- Target See all NAT2 Antibodies
- NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NAT2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE
- Specificity
- Antibody reacts with both NAT1 and NAT2
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against NAT2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NAT2
- Top Product
- Discover our top product NAT2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 290 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Stent-graft repair for thoracic aortic disease: results of an independent nationwide study in France from 1999 to 2001." in: The Journal of thoracic and cardiovascular surgery, Vol. 131, Issue 1, pp. 131-7, (2006) (PubMed).
: "
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Stent-graft repair for thoracic aortic disease: results of an independent nationwide study in France from 1999 to 2001." in: The Journal of thoracic and cardiovascular surgery, Vol. 131, Issue 1, pp. 131-7, (2006) (PubMed).
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- Target
- NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))
- Alternative Name
- NAT2 (NAT2 Products)
- Synonyms
- AAC2 antibody, NAT-2 antibody, PNAT antibody, AV377607 antibody, Nat2a antibody, NAT antibody, AT-2 antibody, AT-B/AT-II antibody, AT-II antibody, AT2 antibody, N-acetyltransferase 2 antibody, N-acetyltransferase 2 (arylamine N-acetyltransferase) antibody, NAT2 antibody, Nat2 antibody
- Background
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NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.
Alias Symbols: AAC2, PNAT
Protein Interaction Partner: APP, NAA10,
Protein Size: 290 - Molecular Weight
- 32 kDa
- Gene ID
- 10
- NCBI Accession
- NM_000015, NP_000006
- UniProt
- P11245
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