ENTPD8 antibody (Ectonucleoside Triphosphate diphosphohydrolase 8) (N-Term)

Details for Product anti-ENTPD8 Antibody No. ABIN2782019, Supplier: Log in to see
Antigen
  • zC10E8.4
  • zgc:92065
  • si:ch211-10e8.4
  • ENTPD1
  • GLSR2492
  • NTPDase-8
  • UNQ2492
  • ectonucleoside triphosphate diphosphohydrolase 8
  • ectonucleoside triphosphate diphosphohydrolase 1
  • ENTPD8
  • entpd8
  • Tsp_07798
  • LOC427778
  • Entpd8
Epitope
N-Term
9
9
8
4
3
2
1
1
Reactivity
Cow (Bovine), Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
34
10
1
1
Host
Rabbit
30
4
Clonality
Polyclonal
Conjugate
This ENTPD8 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
32
21
2
1
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ENTPD8
Blocking Peptide Blocking peptide for this product available: ABIN976366
Sequence IPEAQHRKTP TFLGATAGMR LLSRKNSSQA RDIFAAVTQV LGRSPVDFWG
Predicted Reactivity Cow: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%
Characteristics This is a rabbit polyclonal antibody against ENTPD8. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ENTPD8 (ENTPD8 Antibody Abstract)
Background ENTPD8 is the canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolyzis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. It has activity toward ATP, ADP, UTP and UDP, but not toward AMP.
Alias Symbols: GLSR2492, NTPDase-8, UNQ2492
Protein Size: 495
Molecular Weight 54 kDa
Gene ID 377841
NCBI Accession NM_001033113, NP_001028285
UniProt Q5MY95
Research Area Signaling, Metabolism, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 495 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Ectonucleoside Triphosphate diphosphohydrolase 8 (ENTPD8) (N-Term) antibody (ABIN2782019) WB Suggested Anti-ENTPD8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Munkonda, Kauffenstein, Kukulski, Lévesque, Legendre, Pelletier, Lavoie, Lecka, Sévigny: "Inhibition of human and mouse plasma membrane bound NTPDases by P2 receptor antagonists." in: Biochemical pharmacology, Vol. 74, Issue 10, pp. 1524-34, 2007 (PubMed).

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