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FVT1 antibody (N-Term)

KDSR Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782154
  • Target See all FVT1 (KDSR) Antibodies
    FVT1 (KDSR) (3-Ketodihydrosphingosine Reductase (KDSR))
    Binding Specificity
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Zebrafish (Danio rerio)
    Host
    • 27
    • 2
    Rabbit
    Clonality
    • 27
    • 2
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FVT1 antibody is un-conjugated
    Application
    • 23
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    KKEIEMHSIN DKQVVLCISV DVSQDYNQVE NVIKQAQEKL GPVDMLVNCA
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against KDSR. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of human KDSR
    Top Product
    Discover our top product KDSR Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FVT1 (KDSR) (3-Ketodihydrosphingosine Reductase (KDSR))
    Alternative Name
    KDSR (KDSR Products)
    Synonyms
    fvt1 antibody, zgc:55947 antibody, FVT1 antibody, DHSR antibody, SDR35C1 antibody, 6330410P18Rik antibody, 9430079B08Rik antibody, Fvt1 antibody, 3-ketodihydrosphingosine reductase antibody, kdsr antibody, KDSR antibody, Kdsr antibody
    Background
    The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
    Alias Symbols: DHSR, FVT1, SDR35C1
    Protein Size: 268
    Molecular Weight
    29 kDa
    Gene ID
    2531
    NCBI Accession
    NM_002035, NP_002026
    UniProt
    B4DMX0
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