KNG1 antibody (Middle Region)
-
- Target See all KNG1 Antibodies
- KNG1 (Kininogen 1 (KNG1))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This KNG1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK
- Predicted Reactivity
- Horse: 85%, Human: 100%, Mouse: 77%, Pig: 92%
- Characteristics
- This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KNG1
- Top Product
- Discover our top product KNG1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 644 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
: "
-
Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
-
- Target
- KNG1 (Kininogen 1 (KNG1))
- Alternative Name
- KNG1 (KNG1 Products)
- Synonyms
- BDK antibody, BK antibody, KNG antibody, Kng antibody, KNG2 antibody, fb64g01 antibody, wu:fb64g01 antibody, zgc:103569 antibody, kininogen antibody, bdk antibody, kng antibody, KNG1 antibody, IHRP antibody, KINKG antibody, KINKH antibody, Kng1 antibody, Kngk antibody, kininogen 1 antibody, kininogen 1 L homeolog antibody, inter-alpha-trypsin inhibitor heavy chain family member 4 antibody, kininogen 2-like 1 antibody, KNG1 antibody, Kng1 antibody, kng1 antibody, kng1.L antibody, ITIH4 antibody, Kng2l1 antibody
- Background
-
Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.
Alias Symbols: BDK, KNG
Protein Interaction Partner: Ance, ECE1, COPS6, RXFP4, CPN1, F11, HABP2, CTSK, PREP, MEP1A, ITGB2, GP1BA, KLKB1, KNG1, VTN, THBS1, F2, PLAUR, PLG, KLK1, KRT1, FTL, ELANE, CD93, CTSL, CTSS, CTSG, CAPN2, CAPN1, AGT, APP,
Protein Size: 644 - Molecular Weight
- 72 kDa
- Gene ID
- 3827
- NCBI Accession
- NM_001102416, NP_001095886
- UniProt
- P01042
- Pathways
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
-