Glycogen Synthase 2 antibody (Middle Region)

Catalog No. ABIN2782340

Product Details anti-Glycogen Synthase 2 Antibody

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Dog, Horse, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TLSRAFPDKF HVELTSPPTT EGFKYPRPSS VPPSPSGSQA SSPQSSDVED

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GYS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GYS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 703 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glycogen Synthase 2

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Alternative Name: GYS2 (GYS2 Products)

Synonyms: cb765 antibody, zgc:112057 antibody, BC021322 antibody, LGS antibody, GLYSN antibody, glycogen synthase 2 antibody, gys2 antibody, Gys2 antibody, GYS2 antibody

Background: GYS2 transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Defects in GYS2 are the cause of glycogen storage disease type 0 (GSD0).
Alias Symbols: -
Protein Interaction Partner: GYG2, UBC, TNFRSF1A,
Protein Size: 703

Molecular Weight: 81 kDa

Gene ID: 2998

NCBI Accession: NM_021957, NP_068776

UniProt: P54840

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process