Glycogen Synthase 2 antibody (AA 621-703)

Catalog No. ABIN752173

Product Details anti-Glycogen Synthase 2 Antibody

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Binding Specificity: AA 621-703

Reactivity: Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Pig

Predicted Reactivity: Human,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glycogen synthase 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Glycogen Synthase 2 antibody (ABIN752173)

Scheffler, Park, Roach, Gerrard: "Gain of function AMP-activated protein kinase γ3 mutation (AMPKγ3R200Q) in pig muscle increases glycogen storage regardless of AMPK activation." in: Physiological reports, Vol. 4, Issue 11, (2016) (PubMed).

Target Details for Glycogen Synthase 2

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Alternative Name: Glycogen synthase 2 (GYS2 Products)

Synonyms: cb765 antibody, zgc:112057 antibody, BC021322 antibody, LGS antibody, GLYSN antibody, glycogen synthase 2 antibody, gys2 antibody, Gys2 antibody, GYS2 antibody

Background:

Synonyms: Glycogen starch synthase liver, Glycogen starch synthase liver, EC 2.4.1.11, Glycogen synthase 2 liver, GYS2, GYS2_HUMAN.

Background: Glycogen synthase catalyzes the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.

Gene ID: 2998

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process