IFNGR2 antibody (Middle Region)
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- Target See all IFNGR2 Antibodies
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IFNGR2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- WEKGGIQQVK GPFRSNSISL DNLKPSRVYC LQVQAQLLWN KSNIFRVGHL
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IFNGR2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human IFNGR2
- Top Product
- Discover our top product IFNGR2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 337 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).
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Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).
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- Target
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
- Alternative Name
- IFNGR2 (IFNGR2 Products)
- Synonyms
- Ifgr2 antibody, Ifgt antibody, AF-1 antibody, IFGR2 antibody, IFNGT1 antibody, interferon gamma receptor 2 antibody, Ifngr2 antibody, IFNGR2 antibody, LOC487739 antibody
- Background
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IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AF-1, IFGR2, IFNGT1
Protein Interaction Partner: RPL37A, CAMK2D, ELAVL1, DNAJA3, JAK2, IFNG, NR3C1, ANXA5, IFNGR1,
Protein Size: 337 - Molecular Weight
- 35 kDa
- Gene ID
- 3460
- NCBI Accession
- NM_005534, NP_005525
- UniProt
- P38484
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