ATP5C1 antibody (N-Term)

Catalog No. ABIN2783311

Product Details anti-ATP5C1 Antibody

Target: ATP5C1 (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, gamma Polypeptide 1 (ATP5C1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP5C1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VRNMATLKDI TRRLKSIKNI QKITKSMKMV AAAKYARAER ELKPARVYGT

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Atp5c1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Atp5c1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 298 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP5C1

Target: ATP5C1 (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, gamma Polypeptide 1 (ATP5C1))

Alternative Name: Atp5c1 (ATP5C1 Products)

Synonyms: ATP5C antibody, ATP5CL1 antibody, 1700094F02Rik antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 antibody, ATP5C1 antibody, Atp5c1 antibody

Background: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F1 domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha3beta3. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Alias Symbols: 1700094F02Rik
Protein Interaction Partner: Eed, UBQLN1, SQSTM1, RAD23B, Iqcb1, SNCA,
Protein Size: 298

Molecular Weight: 30 kDa

Gene ID: 11949

NCBI Accession: NM_020615, NP_065640

UniProt: Q91VR2

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process