NEK2 antibody (N-Term)
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- Target See all NEK2 Antibodies
- NEK2 (NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NEK2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RCQKIRRKSD GKILVWKELD YGSMTEAEKQ MLVSEVNLLR ELKHPNIVRY
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against NEK2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human NEK2
- Top Product
- Discover our top product NEK2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 445 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NEK2 (NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))
- Alternative Name
- NEK2 (NEK2 Products)
- Synonyms
- AA617254 antibody, C77054 antibody, HsPK21 antibody, NEK2A antibody, NLK1 antibody, ATNEK2 antibody, NIMA-RELATED KINASE2 antibody, NIMA-related kinase 2 antibody, T9J14.24 antibody, T9J14_24 antibody, NIMA related kinase 2 antibody, NIMA (never in mitosis gene a)-related expressed kinase 2 antibody, NIMA-related kinase 2 antibody, NEK2 antibody, Nek2 antibody
- Background
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This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
Alias Symbols: HsPK21, NEK2A, NLK1
Protein Interaction Partner: ANAPC4, UBC, NEK2, CEP250, CTNNB1, PPP1CC, VCP, CDH1, CDC20, CHEK1, CSN2, CDC27, MYC, PPP1CA, CCDC85A, SPTBN4, GIT1, EDRF1, TCF25, IMMT, NDC80, IFT140, PDE4DIP, TPM3, MCC, EIF4A2, DCTN1, CHGA, Gm9174, Cdc16, Cdc23, NEK11, MAD1L1, PPP1R2, MAPK1, CLEC4C,
Protein Size: 445 - Molecular Weight
- 52 kDa
- Gene ID
- 4751
- NCBI Accession
- NM_002497, NP_002488
- UniProt
- P51955
- Pathways
- M Phase
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