Dnmt2 antibody (N-Term)
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- Target See all Dnmt2 (TRDMT1) Antibodies
- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Dnmt2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MILMSPPCQP FTRIGRQGDM TDSRTNSFLH ILDILPRLQK LPKYILLENV
- Predicted Reactivity
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TRDMT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRDMT1
- Top Product
- Discover our top product TRDMT1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 391 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
- Alternative Name
- TRDMT1 (TRDMT1 Products)
- Synonyms
- MGC89267 antibody, DMNT2 antibody, DNMT2 antibody, MHSAIIP antibody, PUMET antibody, RNMT1 antibody, Dnmt2 antibody, Rnmt2 antibody, dnmt2 antibody, tRNA aspartic acid methyltransferase 1 antibody, tRNA aspartic acid methyltransferase 1 L homeolog antibody, trdmt1 antibody, TRDMT1 antibody, Trdmt1 antibody, trdmt1.L antibody
- Background
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CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: DNMT2, M.HsaIIP, PuMet, RNMT1, DMNT2, PUMET, MHSAIIP
Protein Interaction Partner: TBC1D2B, SNRPD3, NFRKB, GBE1, APP, LRIF1, COPS6, RBM48, SETDB1, UTP14A, DDX24, UNC119, STX1A, EEF1A1,
Protein Size: 391 - Molecular Weight
- 44 kDa
- Gene ID
- 1787
- NCBI Accession
- NM_004412, NP_004403
- UniProt
- O14717
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