Sulfotransferase Family 1E Member 1 (SULT1E1) (Middle Region) antibody

Details for Product No. ABIN2783458, Supplier: Log in to see
Antigen
  • STE
  • St1
  • EST
  • ST1E1
  • Ste
  • EST-1
  • ESTSUL
  • estrogen sulfotransferase
  • sulfotransferase family 1E, estrogen-preferring, member 1
  • sulfotransferase family 1E, member 1
  • ste2
  • SULT1E1
  • St1
  • Sult1e1
  • CpipJ_CPIJ012993
  • CpipJ_CPIJ014515
Alternatives
anti-Human Sulfotransferase Family 1E Member 1 antibody for Immunofluorescence (fixed cells)
Epitope
Middle Region
15
8
7
3
1
1
1
Reactivity
Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
45
21
11
1
1
1
1
Host
Rabbit
37
16
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
30
12
11
10
5
4
3
3
2
2
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SULT1E1
Blocking Peptide Blocking peptide for this product available: ABIN984620
Sequence LMVAGHPNPG SFPEFVEKFM QGQVPYGSWY KHVKSWWEKG KSPRVLFLFY
Predicted Reactivity Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 83%
Characteristics This is a rabbit polyclonal antibody against SULT1E1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SULT1E1 (SULT1E1 Antibody Abstract)
Background Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
Alias Symbols: EST, EST-1, MGC34459, STE, ST1E1
Protein Interaction Partner: PDE9A, LRIF1, COPS6, RBM48, IGSF21, ENOX1, SETDB1, C14orf1, SULT2B1, UNC119, BMPR2, TP53, EEF1A1,
Protein Size: 294
Molecular Weight 35 kDa
Gene ID 6783
NCBI Accession NM_005420, NP_005411
UniProt P49888
Pathways Steroid Hormone Biosynthesis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 294 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Sulfotransferase Family 1E Member 1 (SULT1E1) (Middle Region) antibody (ABIN2783458) WB Suggested Anti-SULT1E1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: <...
Western Blotting (WB) image for anti-Sulfotransferase Family 1E Member 1 (SULT1E1) (Middle Region) antibody (ABIN2783458) WB Suggested Anti-SULT1E1
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500...
Product cited in: Yalcin, Kulkarni, Slitt, King: "Bisphenol A sulfonation is impaired in metabolic and liver disease." in: Toxicology and applied pharmacology, Vol. 292, pp. 75-84, 2016 (PubMed).

Yalcin, More, Neira, Lu, Cherrington, Slitt, King: "Downregulation of sulfotransferase expression and activity in diseased human livers." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 9, pp. 1642-50, 2013 (PubMed).