CHST6 antibody (Middle Region)

Catalog No. ABIN2783540

Product Details anti-CHST6 Antibody

Target: CHST6 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 6 (CHST6))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YAFTGLSLTP QLEAWIHNIT HGSGPGARRE AFKTSSRNAL NVSQAWRHAL

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CHST6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHST6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 395 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHST6

Target: CHST6 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 6 (CHST6))

Alternative Name: CHST6 (CHST6 Products)

Synonyms: mcdc1 antibody, MCDC1 antibody, carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 L homeolog antibody, carbohydrate sulfotransferase 6 antibody, carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 antibody, chst6.L antibody, LOC711570 antibody, CHST6 antibody, LOC100477677 antibody, LOC489707 antibody

Background: CHST6 catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. It mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. CHST6 acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.
Alias Symbols: MCDC1
Protein Size: 395

Molecular Weight: 44 kDa

Gene ID: 4166

NCBI Accession: NM_021615, NP_067628

UniProt: Q9GZX3

Pathways: Glycosaminoglycan Metabolic Process