COL25A1 antibody (Middle Region)
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- Target See all COL25A1 Antibodies
- COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit, Horse, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COL25A1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GERGEAGPPG RGERGEPGAP GPKGKQGESG TRGPKGSKGD RGEKGDSGAQ
- Predicted Reactivity
- Cow: 85%, Dog: 100%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 85%, Rabbit: 86%, Rat: 93%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against COL25A1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human COL25A1
- Top Product
- Discover our top product COL25A1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 642 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))
- Alternative Name
- COL25A1 (COL25A1 Products)
- Synonyms
- COL25A1 antibody, AMY antibody, CLAC antibody, CLAC-P antibody, CLACP antibody, 2700062B08Rik antibody, collagen type XXV alpha 1 chain antibody, collagen, type XXV, alpha 1 antibody, COL25A1 antibody, col25a1 antibody, Col25a1 antibody
- Background
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COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD) brains. COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD, MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]).[supplied by OMIM].
Alias Symbols: CLAC, AMY, CLACP, CLAC-P
Protein Interaction Partner: COL25A1, APP, SNCA, IAPP,
Protein Size: 642 - Molecular Weight
- 64 kDa
- Gene ID
- 84570
- NCBI Accession
- NM_032518, NP_115907
- UniProt
- Q9BXS0
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