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Importin 5 antibody (N-Term)

IPO5 Reactivity: Human, Rat, Mouse, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785469
  • Target See all Importin 5 (IPO5) Antibodies
    Importin 5 (IPO5)
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Rat, Mouse, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse
    Host
    • 37
    • 4
    Rabbit
    Clonality
    • 39
    • 2
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Importin 5 antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    GNNQWPEGLK FLFDSVSSQN VGLREAALHI FWNFPGIFGN QQQHYLDVIK
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against RANBP5. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human RANBP5
    Top Product
    Discover our top product IPO5 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1115 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Importin 5 (IPO5)
    Alternative Name
    RANBP5 (IPO5 Products)
    Synonyms
    IPO5 antibody, RANBP5 antibody, IMB3 antibody, KPNB3 antibody, Pse1 antibody, imp5 antibody, 1110011C18Rik antibody, 5730478E03Rik antibody, AA409333 antibody, C76941 antibody, Kpnb3 antibody, Ranbp5 antibody, importin 5 antibody, IPO5 antibody, Ipo5 antibody
    Background
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
    Alias Symbols: DKFZp686O1576, FLJ43041, IMB3, KPNB3, MGC2068, RANBP5, imp5
    Protein Interaction Partner: HUWE1, UBC, STAU1, ASB15, HK2, HEXB, ATIC, MCTS1, TNFAIP8, EZR, UBA1, TXNRD1, FBXO6, BHLHB9, EGFR, MUC1, SOX2, NPM1, HDAC2, LAS1L, PELP1, WASL, VCAM1, MAP1LC3A, ITGA4, FN1, CFTR, RPL7, CA9, NOTCH1, IPO4, TNPO1, KPNB1, RAN, CUL3, ACD, TINF2, TERF1, BKRF1,
    Protein Size: 1115
    Molecular Weight
    125 kDa
    Gene ID
    3843
    NCBI Accession
    NM_002271, NP_002262
    Pathways
    Protein targeting to Nucleus
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