Arylsulfatase A antibody (Middle Region)
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- Target See all Arylsulfatase A (ARSA) Antibodies
- Arylsulfatase A (ARSA)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Arylsulfatase A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KQLQLLKAQL DAAVTFGPSQ VARGEDPALQ ICCHPGCTPR PACCHCPDPH
- Predicted Reactivity
- Cow: 79%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 79%, Rat: 85%
- Characteristics
- This is a rabbit polyclonal antibody against ARSA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ARSA
- Top Product
- Discover our top product ARSA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 507 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Arylsulfatase A (ARSA)
- Alternative Name
- ARSA (ARSA Products)
- Synonyms
- ARSA antibody, zgc:101575 antibody, arsa antibody, AS-A antibody, ASA antibody, AW212749 antibody, As-2 antibody, As2 antibody, TISP73 antibody, MLD antibody, mld antibody, arylsulfatase A antibody, arylsulfatase antibody, arylsulfatase A, gene 1 S homeolog antibody, ARSA antibody, arsa antibody, arsA antibody, RB6599 antibody, Arsa antibody, arsa.1.S antibody
- Background
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ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD).The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.
Alias Symbols: MLD
Protein Interaction Partner: TRIP13, PPIC, CETN2, CLEC4G, ARSA, GAL3ST1, BMPR2, CTSL,
Protein Size: 507 - Molecular Weight
- 52 kDa
- Gene ID
- 410
- NCBI Accession
- NM_001085427, NP_001078896
- UniProt
- P15289
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