LAMa4 antibody (C-Term)
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- Target See all LAMa4 Antibodies
- LAMa4 (Laminin, alpha 4 (LAMa4))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LAMa4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EVQCPCHCHP AGAPAPPRAV PHSSFSLSPP LSSPQCLESF TWARSVRKLE
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against LAMA4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product LAMa4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 120 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LAMa4 (Laminin, alpha 4 (LAMa4))
- Alternative Name
- LAMA4 (LAMa4 Products)
- Synonyms
- si:dkey-119m7.3 antibody, si:busm1-189a20.2 antibody, CMD1JJ antibody, LAMA3 antibody, LAMA4*-1 antibody, RGD1560062 antibody, laminin subunit alpha 4 antibody, laminin, alpha 4 antibody, LAMA4 antibody, lama4 antibody, Lama4 antibody
- Background
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Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature.
Alias Symbols: DKFZp686D23145, LAMA3, LAMA4*-1
Protein Interaction Partner: RTN4, APC, LRIF1, COPS6, MED31, BRD7, ZHX1, ATF7IP, UBR1, UNC119, TP53, PTN, GAPDH, EEF1A1, TUBB2A,
Protein Size: 120 - Molecular Weight
- 10 kDa
- Gene ID
- 3910
- NCBI Accession
- NM_001105209, NP_001098679
- UniProt
- Q16363
- Pathways
- Brown Fat Cell Differentiation
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