PAD4 antibody (Middle Region)
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- Target See all PAD4 (PADI4) Antibodies
- PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Pig, Sheep, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAD4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TGGISGLDSF GNLEVSPPVT VRGKEYPLGR ILFGDSCYPS NDSRQMHQAL
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against PADI4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PADI4
- Top Product
- Discover our top product PADI4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 663 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking." in: Arthritis research & therapy, Vol. 10, Issue 3, pp. R52, (2008) (PubMed).
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Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking." in: Arthritis research & therapy, Vol. 10, Issue 3, pp. R52, (2008) (PubMed).
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- Target
- PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))
- Alternative Name
- PADI4 (PADI4 Products)
- Synonyms
- PAD antibody, PAD4 antibody, PADI5 antibody, PDI4 antibody, PDI5 antibody, Pad4 antibody, Pdi4 antibody, peptidyl arginine deiminase 4 antibody, peptidyl arginine deiminase, type IV antibody, PADI4 antibody, Padi4 antibody
- Background
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PADI4 is an enzyme responsible for the conversion of arginine residues to citrulline residues. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PAD, PADI5, PDI4, PDI5, PAD4
Protein Interaction Partner: ANXA4, FBXO25, APP, ING4, ELK1, NPM1, TP53, HDAC2, HIST2H3A, HDAC1, TFF1, HIST4H4, HIST3H3,
Protein Size: 663 - Molecular Weight
- 74 kDa
- Gene ID
- 23569
- NCBI Accession
- NM_012387, NP_036519
- UniProt
- Q9UM07
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