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RABGEF1 antibody (N-Term)

RABGEF1 Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Horse, Zebrafish (Danio rerio), Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786039
  • Target See all RABGEF1 Antibodies
    RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
    Binding Specificity
    • 15
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 30
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Goat, Horse, Zebrafish (Danio rerio), Rabbit, Guinea Pig
    Host
    • 28
    • 2
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RABGEF1 antibody is un-conjugated
    Application
    • 24
    • 13
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against RABGEF1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human RABGEF1
    Top Product
    Discover our top product RABGEF1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 491 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
    Alternative Name
    RABGEF1 (RABGEF1 Products)
    Synonyms
    Rab5ef antibody, Rabex5 antibody, Rin2 antibody, RABEX5 antibody, rabex-5 antibody, rabgef1 antibody, RAB guanine nucleotide exchange factor (GEF) 1 antibody, RAB guanine nucleotide exchange factor 1 antibody, RAB guanine nucleotide exchange factor (GEF) 1 L homeolog antibody, Rabgef1 antibody, RABGEF1 antibody, rabgef1.L antibody
    Background
    RABGEF1 forms a complex with rabaptin-5 (RABPT5, MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A, MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
    Alias Symbols: FLJ32302, RABEX5, rabex-5
    Protein Interaction Partner: TRIM15, CIPC, ZC2HC1C, TRIM54, RABGEF1, BLOC1S6, TXN2, THOC1, DAZAP2, UBC, TEAD4, RABEP1, DGCR6, TNKS1BP1, ROCK2, SLMAP, MON1A, RNF11, MON1B, RAB21, UBE2D3, UBE2D1, RAB5A, L1CAM, EEA1, ESR1, EGFR, RAB22A, GGA1, MAPK1, HRAS, YWHAG, YWHAB, KXD1, GGA2, RNF16
    Protein Size: 491
    Molecular Weight
    57 kDa
    Gene ID
    27342
    NCBI Accession
    NM_014504, NP_055319
    UniProt
    A8K3R3
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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