FBXO28 antibody (Middle Region)

Catalog No. ABIN2786088

Product Details anti-FBXO28 Antibody

Target: FBXO28 (F-Box Protein 28 (FBXO28))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO28 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVQEQQKQLQ DQDQKLLEQT QIIGEQNARL AELERKLREV MESAVGNSSG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 75%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against FBXO28. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO28

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 368 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO28

Target: FBXO28 (F-Box Protein 28 (FBXO28))

Alternative Name: FBXO28 (FBXO28 Products)

Synonyms: fd49h06 antibody, wu:fd49h06 antibody, FBXO28 antibody, CENP-30 antibody, Fbx28 antibody, 4833428J17Rik antibody, 5730505P19Rik antibody, D1Ertd578e antibody, mKIAA0483 antibody, F-box protein 28 antibody, F-box protein 28 L homeolog antibody, fbxo28 antibody, fbxo28.L antibody, FBXO28 antibody, Fbxo28 antibody

Background: Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: FLJ10766, Fbx28, KIAA0483, CENP-30
Protein Interaction Partner: PLEKHF2, SDCBP2, SPAG5, SKP1, GOLGA2, PAK1, LYN, HSP90AA1, GK, UBC, PSMB1, Cep55, TRAF2,
Protein Size: 368

Molecular Weight: 41 kDa

Gene ID: 23219

NCBI Accession: NM_015176, NP_055991

UniProt: Q9NVF7