CCNDBP1 antibody (Middle Region)
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- Target See all CCNDBP1 Antibodies
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Cow, Mouse, Rabbit, Dog, Horse, Guinea Pig, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCNDBP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NSAKLVSVLK KALEITKASH VTPQPEDSWI PLLINAIDHC MNRIKELTQS
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against CCNDBP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CCNDBP1
- Top Product
- Discover our top product CCNDBP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 232 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
- Alternative Name
- CCNDBP1 (CCNDBP1 Products)
- Synonyms
- CCNDBP1 antibody, dip1 antibody, gcip antibody, DIP1 antibody, GCIP antibody, HHM antibody, AU022347 antibody, Maid antibody, SECC-8 antibody, SSEC-8 antibody, cyclin D1 binding protein 1 antibody, cyclin D-type binding-protein 1 antibody, CCNDBP1 antibody, ccndbp1 antibody, Ccndbp1 antibody
- Background
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This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
Alias Symbols: DIP1, GCIP, HHM
Protein Interaction Partner: TYMSOS, ZNRF2P1, C6orf226, FAM74A4, ZNF564, ZNF555, TMEM120B, TRAPPC5, RPL39L, ZNF670, NEURL3, ZNF697, ZNF439, C22orf23, ZGPAT, ZNF394, RBP5, FAM110A, THAP7, TTC23, DMRT3, ARHGAP22, CCDC146, ZNF490, THAP10, IMP3, FAM64A, ZNF581, MRPL15, CNNM3, SYF2, NUDCD
Protein Size: 232 - Molecular Weight
- 26 kDa
- Gene ID
- 23582
- NCBI Accession
- NM_037370, NP_411241
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