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COX18 antibody (Middle Region)

COX18 Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786331
  • Target See all COX18 Antibodies
    COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))
    Binding Specificity
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 16
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COX18 antibody is un-conjugated
    Application
    • 6
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    LCSSFVGLSQ NLLLRSPGFR QLCRIPSTKS DSETPYKDIF AAFNTKFISR
    Predicted Reactivity
    Cow: 79%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against COX18. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human COX18
    Top Product
    Discover our top product COX18 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 333 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))
    Alternative Name
    COX18 (COX18 Products)
    Synonyms
    COX18HS antibody, BC038311 antibody, RGD1559547 antibody, COX18 cytochrome c oxidase assembly factor L homeolog antibody, COX18, cytochrome c oxidase assembly factor antibody, cytochrome c oxidase assembly protein 18 antibody, cox18.L antibody, COX18 antibody, Cox18 antibody
    Background
    COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2, MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1248 AY957565.1 1-1248 1249-4523 AC095053.3 75071-78345 c
    Alias Symbols: COX18HS, FLJ38991, MGC126733
    Protein Size: 333
    Molecular Weight
    37 kDa
    Gene ID
    285521
    NCBI Accession
    NM_173827, NP_776188
    UniProt
    Q8N8Q8
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