ASPA antibody (Middle Region)
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- Target See all ASPA Antibodies
- ASPA (Aspartoacylase (ASPA))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ASPA antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IKTSLAPLPC YVYLIEHPSL KYATTRSIAK YPVGIEVGPQ PQGVLRADIL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against ASPA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ASPA
- Top Product
- Discover our top product ASPA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 313 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ASPA (Aspartoacylase (ASPA))
- Alternative Name
- ASPA (ASPA Products)
- Synonyms
- asp antibody, acy2 antibody, ACY-2 antibody, ASP antibody, ACY2 antibody, Acy-2 antibody, Acy2 antibody, nur7 antibody, zgc:171507 antibody, aspartoacylase antibody, Aspartoacylase antibody, ASPA antibody, aspa antibody, Fbal_2465 antibody, Aspa antibody
- Background
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ASPA catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids.This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: ACY2, ASP
Protein Interaction Partner: ACY3, ASPA,
Protein Size: 313 - Molecular Weight
- 36 kDa
- Gene ID
- 443
- NCBI Accession
- NM_000049, NP_000040
- UniProt
- P45381
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