PPP2R5D antibody (Middle Region)

Catalog No. ABIN2787385

Product Details anti-PPP2R5D Antibody

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5D antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ETEAVQMLKD IKKEKVLLRR KSELPQDVYT IKALEAHKRA EEFLTASQEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PPP2R5D. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPP2R5D

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 602 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R5D

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Alternative Name: PPP2R5D (PPP2R5D Products)

Synonyms: B56D antibody, B'delta antibody, TEG-271 antibody, Tex271 antibody, zgc:73160 antibody, zgc:77529 antibody, ppp2r5d antibody, MDS026 antibody, protein phosphatase 2 regulatory subunit B'delta antibody, protein phosphatase 2, regulatory subunit B', delta antibody, serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody, protein phosphatase 2 regulatory subunit Bdelta antibody, PPP2R5D antibody, Ppp2r5d antibody, ppp2r5d antibody, LOC100176996 antibody, PPP2R2D antibody

Background: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: B56D, MGC2134, MGC8949
Protein Interaction Partner: FSD2, USHBP1, PPP2R1A, UBC, NIF3L1, GOPC, SH3GLB1, HECTD1, ARPC2, ARPC1B, TPD52L2, PRDX2, RPA2, RANGAP1, PRDX1, LPP, FEN1, DHPS, YWHAB, SOX2, Dlg4, PPP2R1B, GSK3B, CHEK2, SUMO2, Sgol1, PPP4C, PPP2CB, PPP2CA, PPFIA1, HAND2, HAND1, ARL2, NEK1,
Protein Size: 602

Molecular Weight: 70 kDa

Gene ID: 5528

NCBI Accession: NM_006245, NP_006236

UniProt: Q14738

Pathways: PI3K-Akt Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades