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ATF5 antibody (Middle Region)

ATF5 Reactivity: Human, Mouse, Rat, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787491
  • Target See all ATF5 Antibodies
    ATF5 (Activating Transcription Factor 5 (ATF5))
    Binding Specificity
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 57
    • 34
    • 30
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog
    Host
    • 58
    • 1
    • 1
    Rabbit
    Clonality
    • 48
    • 12
    Polyclonal
    Conjugate
    • 25
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATF5 antibody is un-conjugated
    Application
    • 48
    • 28
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LPPPQQPPPP SPPQPSRLAP YPHPATTRGD RKQKKRDQNK SAALRYRQRK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against ATF5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ATF5
    Top Product
    Discover our top product ATF5 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 282 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wei, Jiang, Liu, Zhou, Chen, Zhang, Zong, Yun, Gu: "Cdc34-mediated degradation of ATF5 is blocked by cisplatin." in: The Journal of biological chemistry, Vol. 283, Issue 27, pp. 18773-81, (2008) (PubMed).

  • Target
    ATF5 (Activating Transcription Factor 5 (ATF5))
    Alternative Name
    ATF5 (ATF5 Products)
    Synonyms
    ATF5 antibody, atfx antibody, hmfn0395 antibody, ATFX antibody, HMFN0395 antibody, AFTA antibody, Atf7 antibody, Atfx antibody, ODA-10 antibody, atf5 antibody, activating transcription factor 5 antibody, activating transcription factor 5, gene 2 S homeolog antibody, ATF5 antibody, atf5 antibody, Atf5 antibody, atf5.2.S antibody
    Background
    ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma.
    Alias Symbols: ATFX, FLJ34666, HMFN0395
    Protein Interaction Partner: CEBPE, CEBPA, GIT2, ATXN1, EP300, CCND3, GABBR2, DISC1, GABBR1, CEBPG, CDC34, TRIB3, UBC, CD34,
    Protein Size: 282
    Molecular Weight
    31 kDa
    Gene ID
    22809
    NCBI Accession
    NM_012068, NP_036200
    UniProt
    B3KND3
    Pathways
    Myometrial Relaxation and Contraction
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