CCR2 antibody (C-Term)
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- Target See all CCR2 Antibodies
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Dog, Cow, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCR2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FTIMIVYFLF WTPYNIVILL NTFQEFFGLS NCESTSQLDQ ATQVTETLGM
- Predicted Reactivity
- Cow: 79%, Dog: 79%, Horse: 79%, Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CCR2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CCR2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 374 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line." in: BMC genomics, Vol. 20, Issue 1, pp. 15, (2019) (PubMed).
: "CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis." in: Veterinary immunology and immunopathology, Vol. 182, pp. 52-58, (2016) (PubMed).
: "
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Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line." in: BMC genomics, Vol. 20, Issue 1, pp. 15, (2019) (PubMed).
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- Target
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Alternative Name
- CCR2 (CCR2 Products)
- Synonyms
- CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody
- Background
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
Alias Symbols: CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2
Protein Size: 374 - Molecular Weight
- 42 kDa
- Gene ID
- 1231
- NCBI Accession
- NM_000647, NP_000638
- UniProt
- P41597
- Pathways
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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