CCR2 antibody

Catalog No. ABIN7193322

Product Details anti-CCR2 Antibody

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD192 expressed in E. coli.

Clone: 3B6B1

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Alternative Name: CD192 (CCR2 Products)

Synonyms: CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody

Background:

Description: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.

Aliases: CCR2, CKR2, CCR-2, CCR2A, CCR2B, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2

Molecular Weight: 41.9 kDa

Gene ID: 729230

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process